Impact of α-synuclein pathology on transplanted hESC-derived dopaminergic neurons in a humanized α-synuclein rat model of PD

Impact of α-synuclein pathology on transplanted hESC-derived dopaminergic neurons in a humanized α-synuclein rat model of PD

Preclinical evaluation of the therapeutic potential of dopamine (DA) neuron alternative in Parkinson’s illness (PD) has primarily been carried out in the 6-hydroxydopamine toxin model. While that is a good model to evaluate graft perform, it doesn’t mirror the pathological options or progressive nature of the illness. In this examine, we set up a humanized […]

Continue Reading